From: Immune profiles of pre-frail people living with HIV-1: a prospective longitudinal study
 | All | Robust | Pre-frail | Difference between pre-frail and non-pre-frail (p) |
---|---|---|---|---|
Sample size, n (%) | 46 | 27 (59%) | 19 (41%) | Â |
Age, years (mean ± SD) | 74.4 ± 3.2 | 73.6 ± 2.6 | 75.5 ± 3.9 | 0.058 |
Female (%) | 4 | 2 (50%) | 2 (50%) | 0.712 |
Waist:Hip ratio (mean ± SD) | 1.00 ± 0.08 | 0.98 ± 0.06 | 1.03 ± 0.10 | 0.299 |
Current CD4 count, cells/µL (mean ± SD) | 592 ± 245 | 622 ± 242 | 550 ± 248 | 0.335 |
Current CD4/CD8 ratio (median [IQR]) | 0.97 [0.64–1.36] | 1.01 [0.76–1.44] | 0.77 [0.54–1.06] | 0.088 |
Pretherapeutic CD4 count, cells/µL (mean ± SD) | 278 ± 171 | 255 ± 141 | 308 ± 206 | 0.353 |
Duration of infection, years (median [IQR]) | 24.5 [19.1–26.8] | 23.8 [13.7–26.7] | 25.0 [23.6–27.2] | 0.778 |
Duration of undetectability, years (mean ± SD) | 8.9 ± 7.2 | 9.3 ± 7.2 | 8.5 ± 7.4 | 0.766 |
Number of comorbidities (median [IQR]) | 4.0 [3.0–5.0] | 4.0 [2.7-5.0] | 4.0 [3.0–6.0] | 0.288 |
EPICES score (mean ± SD) | 22.8 ± 14.8 | 19.4 ± 12.9 | 27.8 ± 16.3 | 0.071 |
VACS index score (median [IQR]) | 39.0 [33.0-47.5] | 38.0 [33.0–43.0] | 39.0 [33.0–52.0] | 0.105 |